Pain management for inflammatory arthritis:Impact of Deniplant remedies intervention

Pain management for inflammatory arthritis:Impact of Deniplant remedies intervention

Major Gheorghe GIURGIU¹,Prof dr Manole COJOCARU^2,3

¹Deniplant-Aide Sante Medical Center, Biomedicine, Bucharest, Romania

deniplant@gmail.com; Telephone: +40 744 827 881

https://orcid.org/0000-0002-5449-2712

²Academy of Romanian Scientists

³Titu Maiorescu University, Faculty of Medicine, Bucharest, Romania

cojocaru.manole@gmail.com; Telephone: +40 723 326 663
https://orcid.org/0000-0002-7192-7490

Background Dysbiosis of the intestinal microbiome is a vital environmental element that triggers the onset of inflammatory arthritis, and dysregulation of the microbiome may result in abnormal immune responses. 

Objectives An intricate relationship between gut microbiome changes and metabolic alterations could help explain the mechanisms by which gut bacteria play roles in the pathogenesis of inflammatory arthritis. To arrive at these observations, we assessed role of Imuniplant, and Artropol in the pain management for inflammatory arthritis.

Materials and methods Currently, disturbance of the gut microbiota has emerged as a novel player involved in the pathogenesis of pain in inflammatory arthritis. With in-depth research, the understanding of the intestinal bacteria-host interaction in pain for inflammatory arthritis is much more comprehensive.

Results A well-functioning immune system is critical for survival. The oral and intestinal microbiomes have a role in the development of inflammatory arthritis. Recent years have also seen an increase in metabolomics studies in inflammatory arthritis with the attempt to identify potential biomarkers for diagnosis or disease activity monitoring. Here, we reviewed the role of dysbiosis of the intestinal microbiome in the aetiology of pain for inflammatory arthritis.

Conclusion A proposed treatment strategy for pain for inflammatory arthritis based on gut microbiome regulation is also discussed in this study. Increasing our understanding of gut microbiota and their function in pain management for inflammatory arthritis will provide us with novel opportunities to develop effective and precise diagnostic strategies and to explore potential microbiota-based treatments for patients with pain in inflammatory arthritis.

Keywords inflammatory arthritis, gut microbiota, immune response, Deniplant intervention